Welcome to the


The Hellenic Complex Systems Laboratory (HCSL) is a virtual, independent, private, non-profit research laboratory, devoted to the transdisciplinary study of the complex systems. It was founded in 1993.

Our research has been focused on the optimization of non-linear multiparameter processes, on the study of the process of the genetic search of the genetic algorithms (GAs), and on the statistics of complexity. In addition, we have been working on the design, evaluation, and optimization of the statistical quality control of the clinical laboratories, on the evaluation and expression of the measurement uncertainty, on the evaluation of the diagnostic accuracy, on the risk management in laboratory medicine, and recently on the research integrity.

Our research and the tools we have developed are based mainly on genetic algorithms, numerical methods, simulation, and symbolic computation.

We have invented the genetic algorithms based design of the statistical quality control (see An introduction to the GAs based QC).

The HCSL has been a founding node of the Network of Excellence in Evolutionary Computing (EvoNet). It has been participating on standards-developing committees of the Clinical and Laboratories Standards Institute (CLSI) and is a member organization of the Consortium for the Barcode of Life (CBOL).